Article
Analysis of association and linkage for the interleukin-4 and interleukin-4 receptor b;alpha; regions in Swedish atopic dermatitis families.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Aug 2002
Söderhäll C, Bradley M, Kockum I, Luthman H, Wahlgren C-F, Nordenskjöld M
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is caused by genetic and environmental factors that interact to determine disease susceptibility and severity. Several lines of evidence suggest that the IL-4 gene and the IL-4-receptor alpha (IL-4Ralpha) gene are involved in the development of atopic diseases. OBJECTIVE: The objective of this study was to evaluate the possible involvement of the chromosomal regions 5q31 and...
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