Article
Association of toll-interacting protein gene polymorphisms with atopic dermatitis.
BMC dermatology - 16 Mar 2007
Schimming Tobias T, Parwez Qumar, Petrasch-Parwez Elisabeth, Nothnagel Michael, Epplen Joerg T, Hoffjan Sabine
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin disorder, affecting up to 15% of children in industrialized countries. Toll-interacting protein (TOLLIP) is an inhibitory adaptor protein within the toll-like receptor (TLR) pathway, a part of the innate immune system that recognizes structurally conserved molecular patterns of microbial pathogens, leading to an inflammatory immune response....
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