Article
Association between genes encoding components of the IL-4/IL-4 receptor pathway and dermatitis in children.
Gene - 25 Jul 2014
Hussein Yousri M, Shalaby Sally M, Nassar Amani, Alzahrani Saad S, Alharbi Ayman S, Nouh Maha
Abstract excerpt
OBJECTIVE: To determine whether IL-4, IL-4Rα and STAT6 polymorphisms are associated with susceptibility to dermatitis in Egyptian children. METHODS: We genotyped three groups of children, consisting of 106 atopic dermatitis (AD) children, 95 non-AD children, and 100 of healthy controls, for IL-4 (-590 C/T), (-33 C/T), IL-4Rα (I50V), (Q576R) and STAT6 (2964 G/A), (2892 C/T) gene polymorphisms using PCR-RFLP assay....
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