Article
Linkage and allelic association of atopy and markers flanking the IL4-receptor gene.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Feb 1998
Deichmann K A, Heinzmann A, Forster J, Dischinger S, Mehl C, Brueggenolte E, Hildebrandt F, Moseler M, Kuehr J
Abstract excerpt
BACKGROUND: Atopy, a clinical syndrome characterized by heightened IgE responsiveness, is largely determined by genetic factors. The disease may well be heterogeneous but the mode of inheritance is unknown. Several genes have been named which affected IgE responsiveness. However, results are conflicting reflecting heterogeneity and a complicated inheritance pattern of the atopic syndrome. In 1994 linkage of the...
Topics
- Adolescent
- Adult
- Alleles
- Child
- Chromosomes, Human, Pair 16
- Family Health
- Female
- Genetic Linkage
- Genetic Markers
- Humans
- Hypersensitivity, Immediate
- Immunoglobulin E
- Male
- Receptors, Interleukin-4