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Article

aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization.

Journal of cell science - 15 Sept 2002

Suzuki Atsushi, Ishiyama Chikako, Hashiba Katsutaka, Shimizu Miki, Ebnet Klaus, Ohno Shigeo

Abstract excerpt

We have previously shown that aPKC interacts with cell polarity proteins PAR-3 and PAR-6 and plays an indispensable role in cell polarization in the C. elegans one-cell embryo as well as in mammalian epithelial cells. Here, to clarify the molecular basis underlying this aPKC function in mammalian epithelial cells, we analyzed the localization of aPKC and PAR-3 during the cell repolarization process accompanied by...

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Identifiers

PMID: 12186943
DOI: 10.1242/jcs.00032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization.PMID 12186943Read ↗

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