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Article

Enforced expression of HOX11 is associated with an immature phenotype in J2E erythroid cells.

British journal of haematology - 1 Sept 2002

Greene Wayne K, Ford Jette, Dixon Darcelle, Tilbrook Peta A, Watt Paul M, Klinken S Peter, Kees Ursula R

Abstract excerpt

The HOX11 gene encodes a homeodomain transcription factor that is essential for spleen development during embryogenesis. HOX11 is also leukaemogenic, both through its clinical association with childhood T-cell acute lymphoblastic leukaemia, and its ability to immortalize other haematopoietic cell lineages experimentally. To examine the pathological role of HOX11 in tumorigenesis, we constitutively expressed HOX11...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

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Source

Identifiers

PMID: 12181065
DOI: 10.1046/j.1365-2141.2002.03704.x

Genes

EPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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