Article
During EPO or anemia challenge, erythroid progenitor cells transit through a selectively expandable proerythroblast pool.
Blood - 9 Dec 2010
Dev Arvind, Fang Jing, Sathyanarayana Pradeep, Pradeep Anamika, Emerson Christine, Wojchowski Don M
Abstract excerpt
Investigations of bone marrow (BM) erythroblast development are important for clinical concerns but are hindered by progenitor cell and tissue availability. We therefore sought to more specifically define dynamics, and key regulators, of the formation of developing BM erythroid cell cohorts. A unique Kit(-)CD71(high)Ter119(-) "stage E2" proerythroblast pool first is described, which (unlike its Kit(+) "stage E1"...
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