Article
Typing for all known MICA alleles by group-specific PCR and SSOP.
Human immunology - 1 Jun 2001
Zhang Y, Lazaro A M, Lavingia B, Stastny P
Abstract excerpt
Major histocompatibility complex class I chain-related gene (MICA) is a recently discovered polymorphic gene in the HLA region expressed mainly by certain epithelial cells, keratinocytes, endothelial cells, fibroblasts, and monocytes. MICA is structurally quite different from the HLA class I genes and is potentially associated with some diseases and with immune response to transplants. Some DNA-based typing...
Topics
- Alleles
- HLA-B Antigens
- HT29 Cells
- HeLa Cells
- Histocompatibility Antigens Class I
- Histocompatibility Testing
- Humans
- Linkage Disequilibrium
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- U937 Cells