Article
MICB Allele Genotyping on Microarrays by Improving the Specificity of Extension Primers.
PloS one - 1 Jan 2015
Baek In-Cheol, Jang Jung-Pil, Choi Eun-Jeong, Kim Tai-Gyu
Abstract excerpt
Major histocompatibility complex (MHC) class I chain-related gene B (MICB) encodes a ligand for activating NKG2D that expressed in natural killer cells, γδ T cells, and αβ CD8+ T cells, which is associated with autoimmune diseases, cancer, and infectious diseases. Here, we have established a system for genotyping MICB alleles using allele-specific primer extension (ASPE) on microarrays. Thirty-six high quality,...
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