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Distributions of MICA and MICB Alleles Typed by Amplicon-Based Next-Generation Sequencing in South Koreans.

HLA - 1 Oct 2024

Choi Eun-Jeong, Kim Hyoung-Jae, Kim Jin-Hyeok, Baek In-Cheol

Abstract excerpt

Major histocompatibility complex class I chain-related genes A and B (MICA and MICB) play a role as ligands in activating the NKG2D receptor expressed in natural killer cells, γδ T-cells and αβ CD8 T-cells and have been defined in human diseases and haematopoietic stem cell transplantation (HSCT). MICA and MICB alleles were genotyped at the three-field level by amplicon-based next-generation sequencing (NGS)...

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Identifiers

PMID: 39470005
DOI: 10.1111/tan.15735

Genes

MICA
MICB

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