Article
Sequencing-based typing reveals six novel MHC class I chain-related gene B (MICB) alleles.
Tissue antigens - 1 Jun 1998
Visser C J, Tilanus M G, Schaeffer V, Tatari Z, Tamouza R, Janin A, Charron D
Abstract excerpt
The MHC class I chain-related gene A (MICA) is highly polymorphic. In this paper we demonstrate polymorphism in the other expressing member of the MIC family of genes: MICB. Using a sequencing-based typing approach on cDNA, analysis of exons 2 through 6 revealed eight polymorphic sites resulting...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Breast Neoplasms
- Exons
- Female
- Genes, MHC Class I
- HLA-A2 Antigen
- Histocompatibility Antigens Class I
- Histocompatibility Testing
- Humans
- Molecular Sequence Data
- Polymorphism, Genetic
- Sequence Homology, Amino Acid