Article
Sequencing-based typing reveals six novel MHC class I chain-related gene B (MICB) alleles.
Tissue antigens - 1 Jun 1998
Visser C J, Tilanus M G, Schaeffer V, Tatari Z, Tamouza R, Janin A, Charron D
Abstract excerpt
The MHC class I chain-related gene A (MICA) is highly polymorphic. In this paper we demonstrate polymorphism in the other expressing member of the MIC family of genes: MICB. Using a sequencing-based typing approach on cDNA, analysis of exons 2 through 6 revealed eight polymorphic sites resulting in six unique MICB sequences. Although MICB has high nucleotide homology with MICA, its polymorphism is restricted and...
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