Article
Basal core promoter and precore mutations among hepatitis B virus circulating in Brazil and its association with severe forms of hepatic diseases.
Memorias do Instituto Oswaldo Cruz - 1 Sept 2017
Chachá Silvana Gama Florencio, Gomes-Gouvêa Michele Soares, Malta Fernanda de Mello, Ferreira Sandro da Costa, Villanova Márcia Guimarães, Souza Fernanda Fernandes, Teixeira Andreza Correa, Passos Afonso Dinis da Costa, Pinho João Renato Rebello, Martinelli Ana de Lourdes Candolo
Abstract excerpt
BACKGROUND: In Brazil, few studies have investigated the prevalence of infection with the precore (PC) and basal core promoter (BCP) mutants of the hepatitis B virus (HBV). OBJECTIVES: This study aimed to analyse the frequency of PC and BCP mutations among patients infected with HBV and to evaluate the association between the variants and advanced hepatic disease. METHODS: A total of 161 patients infected with...
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