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Article

Clinical significance of precore and core promoter mutations in genotype D hepatitis B-related chronic liver disease.

Journal of viral hepatitis - 1 Oct 2008

Poustchi H, Mohamadkhani A, Bowden S, Montazeri G, Ayres A, Revill P, Farrell G C, Locarnini S, George J, Malekzadeh R

Abstract excerpt

SUMMARY: The impact of mutations in the precore and basal core promoter (BCP) regions of the hepatitis B virus on the course of chronic liver disease is not well established. We sought to examine the relationship of these characteristics to the clinical expression of liver disease in patients infected with genotype D chronic hepatitis B (CHB). BCP and precore mutations in 110 patients with genotype D1 CHB were...

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Share to DNA, Viral
Share to Hepatitis B, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B Core Antigens

Share to Hepatitis B virus

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 18507754
DOI: 10.1111/j.1365-2893.2008.00998.x

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