Article
Comparative study of genotype B and C hepatitis B virus-induced chronic hepatitis in relation to the basic core promoter and precore mutations.
Journal of gastroenterology and hepatology - 1 Mar 2005
Watanabe Koji, Takahashi Toru, Takahashi Sumio, Okoshi Shogo, Ichida Takafumi, Aoyagi Yutaka
Abstract excerpt
BACKGROUND: The clinicopathological profiles and outcome of chronic hepatitis B can differ by hepatitis B virus (HBV) genotypes. In Japan, genotype B and C are two major HBV genotypes. The basic core promoter and precore mutations are other known viral factors for disease activity, although the relationship between HBV genotypes and these mutations is not fully understood. METHODS: The HBV genotypes in 90...
Topics
- Adult
- Alanine Transaminase
- Aspartate Aminotransferases
- Biomarkers
- Biopsy
- DNA, Viral
- Enzyme-Linked Immunosorbent Assay
- Female
- Follow-Up Studies
- Genome, Viral
- Genotype
- Hepacivirus
- Hepatitis B Core Antigens