Article
Robust TDT-type candidate-gene association tests.
Annals of human genetics - 1 Mar 2002
Zheng G, Freidlin B, Gastwirth J L
Abstract excerpt
In studies of association between genetic markers and a disease, the transmission disequilibrium test (TDT) has become a standard procedure. It was introduced originally as a test for linkage in the presence of association and can be used as a test for association under appropriate assumptions. The power of the TDT test for association between a candidate gene and disease depends on the underlying genetic model...
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