Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A robust genome-wide scan statistic of the Wellcome Trust Case-Control Consortium.

Biometrics - 1 Dec 2009

Joo Jungnam, Kwak Minjung, Ahn Kwangmi, Zheng Gang

Abstract excerpt

In genome-wide association (GWA) studies, test statistics that are efficient and robust across various genetic models are preferable, particularly for studying multiple diseases in the Wellcome Trust Case-Control Consortium (WTCCC, 2007, Nature 447, 661-678). A new test statistic, the minimum of the p-values of the trend test and Pearson's test, was considered by the WTCCC. It is referred to here as MIN2. Because...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biometry
Share to Case-Control Studies
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genome-Wide Association Study

Share to Models, Genetic

Share to Models, Statistical

Share to United Kingdom

Source

Identifiers

PMID: 19432787
DOI: 10.1111/j.1541-0420.2009.01185.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A robust genome-wide scan statistic of the Wellcome Trust Case-Control Consortium.PMID 19432787Read ↗

GWAR: robust analysis and meta-analysis of genome-wide association studies.Semantic proximity Read ↗

A unifying framework for robust association testing, estimation, and genetic model selection using the generalized linear model.Semantic proximity Read ↗

MAX-rank: a simple and robust genome-wide scan for case-control association studies.Semantic proximity Read ↗

Robust tests for single-marker analysis in case-control genetic association studies.Semantic proximity Read ↗

Robust joint analysis allowing for model uncertainty in two-stage genetic association studies.Semantic proximity Read ↗

Robust association tests under different genetic models, allowing for binary or quantitative traits and covariates.Semantic proximity Read ↗

Efficient approximation of P-value of the maximum of correlated tests, with applications to genome-wide association studies.Semantic proximity Read ↗

A robust test for two-stage design in genome-wide association studies.Semantic proximity Read ↗

Pearson's test, trend test, and MAX are all trend tests with different types of scores.Semantic proximity Read ↗

Robust Mantel-Haenszel test under genetic model uncertainty allowing for covariates in case-control association studies.Semantic proximity Read ↗

CMAX3: A Robust Statistical Test for Genetic Association Accounting for Covariates.Semantic proximity Read ↗

Improving power for testing genetic association in case-control studies by reducing the alternative space.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.