Article
Tests for candidate-gene association using case-parents design.
Annals of human genetics - 1 Nov 2003
Zheng G, Chen Z, Li Z
Abstract excerpt
In the case-parents design for testing candidate-gene association, the conditional likelihood method based on genotype relative risks has been developed recently. A specific relation of the genotype relative risks is referred to as a genetic model. The efficient score tests have been used when the genetic model is correctly specified under the alternative hypothesis. In practice, however, it is usually not able...
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