Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adaptive transmission disequilibrium test for family trio design.

Statistical applications in genetics and molecular biology - 1 Jan 2009

Yuan Min, Tian Xin, Zheng Gang, Yang Yaning

Abstract excerpt

The transmission disequilibrium test (TDT) is a standard method to detect association using family trio design. It is optimal for an additive genetic model. Other TDT-type tests optimal for recessive and dominant models have also been developed. Association tests using family data, including the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Chromosomes, Human, Pair 6
Share to Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DR Antigens

Share to Inheritance Patterns

Share to Lod Score

Share to Models, Statistical

Share to Research Design

Source

Identifiers

PMID: 19572829
DOI: 10.2202/1544-6115.1451

Genes

MAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19572829-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adaptive transmission disequilibrium test for family trio design.PMID 19572829Read ↗

Adaptive robust genetic association tests using case-parents triad families.Semantic proximity Read ↗

A simple and robust TDT-type test against genotyping error with error rates varying across families.Semantic proximity Read ↗

The power of the transmission disequilibrium test (TDT) with both case-parent and control-parent trios.Semantic proximity Read ↗

Screening and replication using the same data set: testing strategies for family-based studies in which all probands are affected.Semantic proximity Read ↗

Using unaffected child trios to test for transmission distortion.Semantic proximity Read ↗

Including non-informative parents in transmission-based association tests.Semantic proximity Read ↗

Design efficiency in genetic association studies.Semantic proximity Read ↗

A general framework for robust and efficient association analysis in family-based designs: quantitative and dichotomous phenotypes.Semantic proximity Read ↗

Testing for genetic association with constrained models using triads.Semantic proximity Read ↗

Method for using complete and incomplete trios to identify genes related to a quantitative trait.Semantic proximity Read ↗

Assessing genuine parents-offspring trios for genetic association studies.Semantic proximity Read ↗

Adaptive weighted sum tests via LASSO method in multi-locus family-based association analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.