Article
DNA-damage induction of RAD54 can be regulated independently of the RAD9- and DDC1-dependent checkpoints that regulate RNR2.
Current genetics - 1 Jul 2002
Walsh Lindsey, Schmuckli-Maurer Jacqueline, Billinton Nicholas, Barker M Gordon, Heyer Wolf-Dietrich, Walmsley Richard M
Abstract excerpt
DNA damage checkpoints regulate a number of physiological responses after DNA damage. The transcriptional level of many genes is specifically induced in response to genotoxic stress in a checkpoint-dependent manner. The regulation of DNA damage-induced transcription of RAD54 and RNR2 by RAD9, DDC1, DUN1, CRT1 and MBP1 was investigated in Saccharomyces cerevisiae, using green fluorescent protein reporter assays...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
