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Article

PTEN, DMBT1, and p16 alterations in diffusely infiltrating astrocytomas.

International journal of oncology - 1 Sept 2002

Fan Xing, Muñoz Jorge, Sanko Stephen G, Castresana Javier S

Abstract excerpt

Losses at chromosomes 10q and 9p are genetic events implicated in the genesis of diffusely infiltrating astrocytomas. We studied the role of PTEN (10q23.3), DMBT1 (10q25.3-26.1) and p16 (9p21) tumor suppressor genes in a series of 50 low- and high-grade astrocytomas. A genetic screening for point mutations, homozygous deletions and promoter hypermethylation was done by PCR-SSCP, direct sequencing, differential...

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Source

Identifiers

PMID: 12168116

Genes

DMBT1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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