Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pilocytic astrocytomas do not show most of the genetic changes commonly seen in diffuse astrocytomas.

Histopathology - 1 Nov 2000

Cheng Y, Pang J C, Ng H K, Ding M, Zhang S F, Zheng J, Liu D G, Poon W S

Abstract excerpt

AIMS: While it is well known that pilocytic astrocytomas are clinically distinct from diffuse astrocytomas, few comprehensive studies have focused on their genetic differences. The aim of this study was to examine pilocytic astrocytomas for genetic alterations that are commonly seen in diffuse astrocytomas. METHODS AND RESULTS: By using molecular genetic and immunohistochemical techniques, we evaluated p16, p53,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytoma
Share to Cyclin-Dependent Kinase 4
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinases

Share to Immunoenzyme Techniques

Share to Loss of Heterozygosity

Share to Phosphoric Monoester Hydrolases

Share to PTEN Phosphohydrolase

Source

Identifiers

PMID: 11119125
DOI: 10.1046/j.1365-2559.2000.01005.x

Genes

PTEN
CDK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pilocytic astrocytomas do not show most of the genetic changes commonly seen in diffuse astrocytomas.PMID 11119125Read ↗

Pilocytic astrocytoma: pathology, molecular mechanisms and markers.Semantic proximity Read ↗

PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma.Semantic proximity Read ↗

Adult pilocytic astrocytomas: clinical features and molecular analysis.Semantic proximity Read ↗

V600E BRAF mutation in pilocytic astrocytoma is associated with a more diffuse growth pattern but does not confer a more aggressive clinical behavior.Semantic proximity Read ↗

Genetic alterations commonly found in diffusely infiltrating cerebral gliomas are rare or absent in pleomorphic xanthoastrocytomas.Semantic proximity Read ↗

Distinct Genetic Signatures among Pilocytic Astrocytomas Relate to Their Brain Region OriginSemantic proximity Read ↗

Absence of mutation of the p73 gene in astrocytic neoplasms.Semantic proximity Read ↗

Integrated DNA methylation analysis identifies topographical and tumoral biomarkers in pilocytic astrocytomasSemantic proximity Read ↗

High frequency of p53 protein accumulation without p53 gene mutation in human juvenile pilocytic, low grade and anaplastic astrocytomas.Semantic proximity Read ↗

BRAF alterations are frequent in cerebellar low-grade astrocytomas with diffuse growth pattern.Semantic proximity Read ↗

Molecular pathogenesis of astrocytic tumours.Semantic proximity Read ↗

IDH-1 polymorphisms in pilocytic astrocytomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.