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Article

Ribosomal proteins mediate the hepatitis C virus IRES-HeLa 40S interaction.

RNA (New York, N.Y.) - 1 Jul 2002

Otto Geoff A, Lukavsky Peter J, Lancaster Alissa M, Sarnow Peter, Puglisi Joseph D

Abstract excerpt

Translation of the hepatitis C virus genomic RNA is mediated by an internal ribosome entry site (IRES). The 330-nt IRES RNA forms a binary complex with the small 40S ribosomal subunit as a first step in translation initiation. Here chemical probing and 4-thiouridine-mediated crosslinking are used...

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Identifiers

PMID: 12166646
DOI: 10.1017/s1355838202022057
PMCID: PMC1370308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12166646-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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