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Article

Structure of the Hepatitis C Virus IRES Bound to the Human 80S Ribosome: Remodeling of the HCV IRES

1 Nov 2005

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Share to RNA and protein synthesis mechanisms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16271893
DOI: 10.1016/j.str.2005.08.008

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure of the Hepatitis C Virus IRES Bound to the Human 80S Ribosome: Remodeling of the HCV IRESPMID 16271893Read ↗

Cryo-EM structure of Hepatitis C virus IRES bound to the human ribosome at 3.9-Å resolutionSemantic proximity Read ↗

HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation.Semantic proximity Read ↗

LOOP IIId of the HCV IRES is essential for the structural rearrangement of the 40S-HCV IRES complex.Semantic proximity Read ↗

Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunitSemantic proximity Read ↗

Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRESSemantic proximity Read ↗

Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and functionSemantic proximity Read ↗

HCV and CSFV IRES domain II mediate eIF2 release during 80S ribosome assemblySemantic proximity Read ↗

Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNASemantic proximity Read ↗

Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiationSemantic proximity Read ↗

A conserved RNA structure within the HCV IRES eIF3-binding siteSemantic proximity Read ↗

Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodelingSemantic proximity Read ↗

The hepatitis C virus internal ribosome-entry site: a new target for antiviral researchSemantic proximity Read ↗

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