Article
Single-nucleotide polymorphisms in the promoter region of the PARKIN gene and Parkinson's disease.
Neuroscience letters - 30 Aug 2002
Mata Ignacio F, Alvarez Victoria, García-Moreira Vanessa, Guisasola Luis M, Ribacoba René, Salvador Carlos, Blázquez Marta, Sarmiento Rogelio González, Lahoz Carlos H, Menes Bernardino B, García Eliecer Coto
Abstract excerpt
Mutations in the PARKIN gene have been identified in families with recessively inherited Parkinson disease (PD). Common DNA-polymorphisms at the PARKIN gene could contribute to the risk for PD in the general population. Here we searched for DNA-polymorphisms in the PARKIN promoter. We found two single nucleotide polymorphisms (-324 A/G and -797 A/G). In order to analyse the association of PD with these and two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.