Article
Coding polymorphisms in the parkin gene and susceptibility to Parkinson disease.
Archives of neurology - 1 Sept 2003
Lücking Christoph-Burkhard, Chesneau Véronique, Lohmann Ebba, Verpillat Patrice, Dulac Cyprien, Bonnet Anne-Marie, Gasparini Francesca, Agid Yves, Dürr Alexandra, Brice Alexis
Abstract excerpt
BACKGROUND: Mutations in the parkin gene, an E3 protein-ubiquitin ligase, cause autosomal recessive early-onset Parkinson disease (PD). The role of polymorphisms in the parkin gene as risk factors for PD is still unclear, as the results in the literature are contradictory. PATIENTS: We compared t...
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