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Article

A functional polymorphism in the parkin gene promoter affects the age of onset of Parkinson's disease.

Neuroscience letters - 6 Mar 2007

Sutherland Greg, Mellick George, Sue Carolyn, Chan Daniel K Y, Rowe Dominic, Silburn Peter, Halliday Glenda

Abstract excerpt

Mutations in the parkin gene are the major cause of autosomal recessive early-onset forms of Parkinson's disease (PD). As reduced parkin expression might also affect the clinical course of idiopathic PD we investigated the effect of a low expressing allele in the parkin promoter region on the age...

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Source

Identifiers

PMID: 17280783
DOI: 10.1016/j.neulet.2006.12.051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17280783-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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