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Article

Mycophenolic acid antagonizes the activation of cultured human mesangial cells.

Kidney international - 1 Sept 2002

Dubus Isabelle, Vendrely Benoît, Christophe Isabelle, Labouyrie Jean-Pierre, Delmas Yahsou, Bonnet Jacques, Combe Christian

Abstract excerpt

BACKGROUND: Activation of mesangial cells is observed in several forms of chronic renal disease, and in culture conditions upon stimulation by fetal calf serum (FCS), or agonists such as transforming growth factor beta (TGF-beta). Mycophenolate mofetil (MMF), the precursor of mycophenolic acid (MPA), is currently used in organ transplantation and has been shown to be protective in clinical and experimental...

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PMID: 12164867
DOI: 10.1046/j.1523-1755.2002.00514.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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