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Article

Effect of HMG-CoA reductase inhibitors on proliferation and protein synthesis by rat hepatic stellate cells.

Journal of hepatology - 1 May 2003

Rombouts Krista, Kisanga Elton, Hellemans Karine, Wielant Annemie, Schuppan Detlef, Geerts Albert

Abstract excerpt

BACKGROUND/AIMS: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors called statins, have besides their cholesterol-lowering function, therapeutic value in conditions such as neo-angiogenesis and atherosclerosis. We investigated the effect of two statins on the proliferation rate and protein steady state levels of hepatic stellate cells (HSC). METHODS: Cellular DNA synthesis under the influence of statins...

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Identifiers

PMID: 12713866
DOI: 10.1016/s0168-8278(03)00051-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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