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Article

Mycophenolic acid impedes the antigen presenting and lymph node homing capacities of human blood myeloid dendritic cells.

Transplantation - 27 Aug 2009

Cicinnati Vito R, Hou Jing, Lindemann Monika, Horn Peter A, Sotiropoulos Georgios C, Paul Andreas, Gerken Guido, Beckebaum Susanne

Abstract excerpt

BACKGROUND: Mycophenolic acid (MPA) is the pharmacologically active compound of the immunosuppressive drug mycophenolate mofetil. Dendritic cells (DC) are the key to initiating and priming the adaptive immune response leading to allograft rejection. We investigated the effects of MPA on human blood myeloid DC (MDC) homeostasis with a particular emphasis on their trafficking properties. METHODS: Isolated...

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Source

Identifiers

PMID: 19696633
DOI: 10.1097/TP.0b013e3181b0e608

Genes

CCR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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