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Article

Microsatellite instability is associated with the loss of apoptosis in ductal breast carcinomas.

Breast cancer research and treatment - 1 Jan 2001

Méndez O, Máñas S, Peinado, Fabra A, Escobedo A, Moreno A, Sierra A

Abstract excerpt

Metastatic progression in ductal breast carcinomas are related to apoptosis in primary tumors. Frameshift mutations in a single-repeat sequence within the coding region (G)8 of the pro-apoptotic Bax gene have been related to microsatellite instability (MSI) and progression of some carcinomas and lymphomas. The aim of this study was to explore whether the extended lifespan of breast cancer cells can also be...

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Share to bcl-2-Associated X Protein
Share to Carcinoma, Ductal, Breast

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Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 11261833
DOI: 10.1023/a:1006490622103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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