Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunohistochemical and molecular analysis of bax, bcl-2 and p53 genes in laryngeal squamous cell carcinomas.

Anticancer research - 1 Jan 2000

Fracchiolla N S, Capaccio P, Carboni N, Pagliari A V, Neri A, Ronchett D, Pruner G, Silvotti M G, Pignataro L, Buffa R, Broich G

Abstract excerpt

BACKGROUND: We investigated the role of apoptosis and its potential alterations in laryngeal squamous cell carcinomas (LSCCs) by evaluating bax, bcl-2 and p53 protein expression in 50 cases and by characterising the molecular status of the bax and p53 genes. MATERIAL AND METHODS: p53 and bax gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to bcl-2-Associated X Protein
Share to Carcinoma, Squamous Cell
Share to Genes, bcl-2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Laryngeal Neoplasms

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins c-bcl-2

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 10368653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10368653-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunohistochemical and molecular analysis of bax, bcl-2 and p53 genes in laryngeal squamous cell carcinomas.PMID 10368653Read ↗

Spontaneous apoptosis in laryngeal squamous cell carcinoma is independent of bcl-2 and bax protein expressionSemantic proximity Read ↗

p53, bcl-2 and bax abnormalities in non-Hodgkin's lymphomas of the head and neck.Semantic proximity Read ↗

Overexpression of bax associated with mutations in the loop-sheet-helix motif of p53.Semantic proximity Read ↗

Expression of pro‐apoptotic Bax and anti‐apoptotic Bcl‐2 proteins in human retinoblastomaSemantic proximity Read ↗

Expression of the apoptosis-related oncogenes bcl-2, bax, and p53 in Merkel cell carcinoma: Can they predict treatment response and clinical outcome?Semantic proximity Read ↗

p53 apoptotic response to DNA damage dependent on bcl2 but not bax in head and neck squamous cell carcinoma lines.Semantic proximity Read ↗

Association of Bax Expression and Bcl2/Bax Ratio with Clinical and Molecular Prognostic Markers in Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

Mutant p53 protein, Bcl-2/Bax ratios and apoptosis in paediatric acute lymphoblastic leukaemia.Semantic proximity Read ↗

Prognostic value of immunohistochemical expression of p53, bax, Bcl‐2 and Bcl‐x<sub>L</sub> in resected non‐small‐cell lung cancersSemantic proximity Read ↗

Expression of apoptosis regulatory proteins of the Bcl-2 family and p53 in primary resected non-small-cell lung cancerSemantic proximity Read ↗

Bax mutations are an infrequent event in indolent lymphomas and in mantle cell lymphoma.Semantic proximity Read ↗

Prognostic value of p53 mutations, bax, and spontaneous apoptosis in maxillary sinus squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.