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Article

A myelin galactolipid, sulfatide, is essential for maintenance of ion channels on myelinated axon but not essential for initial cluster formation.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Aug 2002

Ishibashi Tomoko, Dupree Jeffrey L, Ikenaka Kazuhiro, Hirahara Yukie, Honke Koichi, Peles Elior, Popko Brian, Suzuki Kinuko, Nishino Hitoo, Baba Hiroko

Abstract excerpt

Myelinated axons are divided into four distinct regions: the node of Ranvier, paranode, juxtaparanode, and internode, each of which is characterized by a specific set of axonal proteins. Voltage-gated Na+ channels are clustered at high densities at the nodes, whereas shaker-type K+ channels are concentrated at juxtaparanodal regions. These channels are separated by the paranodal regions, where septate-like...

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Share to Cell Adhesion Molecules, Neuronal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12151530
PMCID: PMC6758132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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