Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunomodulatory effects of antigen-pulsed macrophages in a murine model of allergic asthma.

American journal of respiratory cell and molecular biology - 1 Aug 2002

Janssen Edith M, Wauben Marca H M, Nijkamp Frans P, van Eden Willem, van Oosterhout Antoon J M

Abstract excerpt

Macrophages (Mphi) play an unique role in the activation and regulation of T cells through their ability to modulate specific costimulatory and cytokine signals. Here we investigated the immunomodulatory effects of allergen presentation by Mphi in a murine model of allergic asthma. Purified peritoneal Mphi were pulsed with ovalbumin (OVA) (OVA-Mphi), or the immunodominant epitope OVA(323-339) (OVA(323-339)-Mphi),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adjuvants, Immunologic
Share to Antigen Presentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens

Share to Bronchial Hyperreactivity

Share to Interferon-gamma

Share to Interleukin-10

Share to Macrophages, Peritoneal

Share to Ovalbumin

Source

Identifiers

PMID: 12151319
DOI: 10.1165/ajrcmb.27.2.4788

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunomodulatory effects of antigen-pulsed macrophages in a murine model of allergic asthma.PMID 12151319Read ↗

Explaining the polarized macrophage pool during murine allergic lung inflammationSemantic proximity Read ↗

Anti-inflammatory activity of inhaled mometasone furoate in allergic mice.Semantic proximity Read ↗

Liposomes of phosphatidylcholine and cholesterol induce an M2-like macrophage phenotype reprogrammable to M1 pattern with the involvement of B-1 cells.Semantic proximity Read ↗

Conjunctival macrophages act as antigen-presenting cells in the conjunctiva during the development of experimental allergic conjunctivitis.Semantic proximity Read ↗

Increase in a distinct pulmonary macrophage subset possessing an antigen-presenting cell phenotype and in vitro APC activity following silica exposure.Semantic proximity Read ↗

T cells are necessary for Th2 cytokine production and eosinophil accumulation in airways of antigen-challenged allergic mice.Semantic proximity Read ↗

Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation.Semantic proximity Read ↗

The Role of Alveolar Epithelial Type II-Like Cells in Uptake of Structurally Different Antigens and in Polarisation of Local Immune Responses.Semantic proximity Read ↗

Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells.Semantic proximity Read ↗

Ovalbumin (OVA) and Mycobacterium tuberculosis bacilli cooperatively polarize anti-OVA T-helper (Th) cells toward a Th1-dominant phenotype and ameliorate murine tracheal eosinophilia.Semantic proximity Read ↗

Expression of costimulatory molecules on alveolar macrophages in hypersensitivity pneumonitis.Semantic proximity Read ↗

Adoptive transfer of T-helper cell type 1 clones attenuates an asthmatic phenotype in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.