Article
The Role of Alveolar Epithelial Type II-Like Cells in Uptake of Structurally Different Antigens and in Polarisation of Local Immune Responses.
PloS one - 1 Jan 2015
Akgün Johnnie, Schabussova Irma, Schwarzer Martin, Kozakova Hana, Kundi Michael, Wiedermann Ursula
Abstract excerpt
BACKGROUND: Our previous studies on intranasal tolerance induction demonstrated reduction of allergic responses with different allergen constructs. The underlying mechanisms varied depending on their conformation or size. OBJECTIVE: The aim of the present study was to compare the uptake of two structurally different allergen molecules within the respiratory tract following intranasal application. METHODS: The...
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