Article
Conjunctival macrophages act as antigen-presenting cells in the conjunctiva during the development of experimental allergic conjunctivitis.
Molecular vision - 10 Jul 2010
Ishida Waka, Fukuda Ken, Kajisako Mina, Takahashi Ayako, Sumi Tamaki, van Rooijen Nico, Fukushima Atsuki
Abstract excerpt
PURPOSE: Antigen (Ag)-presenting cells (APCs) participate in the development of allergic conjunctivitis (AC). However, the conjunctival APCs that take up Ag in AC have not been identified. We sought to clarify the phenotypes of conjunctival APCs that take up, process, and present Ag to T cells during the development of experimental AC. METHODS: Splenocytes from naïve ovalbumin (OVA)-specific T cell receptor...
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