Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells.

The Journal of experimental medicine - 19 Jul 1999

Iwasaki A, Kelsall B L

Abstract excerpt

Orally administered antigens often generate immune responses that are distinct from those injected systemically. The role of antigen-presenting cells in determining the type of T helper cell response induced at mucosal versus systemic sites is unclear. Here we examine the phenotypic and functional differences between dendritic cells (DCs) freshly isolated from Peyer's patches (PP) and spleen (SP). Surface...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Dendritic Cells
Share to Interleukin-10

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-4

Share to Peyer's Patches

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to Spleen

Share to Th2 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 10432286
DOI: 10.1084/jem.190.2.229
PMCID: PMC2195574

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells.PMID 10432286Read ↗

Tissue-specific antigen-presenting cells contribute to distinct phenotypes of allergy.Semantic proximity Read ↗

CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo.Semantic proximity Read ↗

Depending on their maturation state, splenic dendritic cells induce the differentiation of CD4(+) T lymphocytes into memory and/or effector cells in vivo.Semantic proximity Read ↗

Mucosal immunity and inflammation. I. Mucosal dendritic cells: their specialized role in initiating T cell responses.Semantic proximity Read ↗

Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells.Semantic proximity Read ↗

Characterization of dendritic cells in humans with type 1 diabetes.Semantic proximity Read ↗

Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets.Semantic proximity Read ↗

Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells.Semantic proximity Read ↗

Dendritic cells of the oral mucosa.Semantic proximity Read ↗

Therapeutic potential of tolerogenic dendritic cells in IBD: from animal models to clinical application.Semantic proximity Read ↗

Activation of purified allogeneic CD4(+) T cells by rat bone marrow-derived dendritic cells induces concurrent secretion of IFN-gamma, IL-4, and IL-10.Semantic proximity Read ↗

Induction of type 2 T helper cell allergen tolerance by IL-10-differentiated regulatory dendritic cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.