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Article

Anti-inflammatory activity of inhaled mometasone furoate in allergic mice.

Arzneimittel-Forschung - 1 Apr 1998

Chapman R W, Sehring S J, Garlisi C G, Falcone A, Kung T T, Stelts D, Minnicozzi M, Jones H, Umland S, Egan R W, Kreutner W

Abstract excerpt

Mometasone furoate (CAS 83919-23-7, Sch 32088) is a new inhaled corticosteroid that is being developed to treat allergic inflammatory airway disorders such as rhinitis and asthma. In this study, we investigated the effects of inhaled mometasone furoate in allergic mice that, after antigen challenge, develop an influx of eosinophils and T cells and display an increased mRNA expression of proinflammatory cytokines...

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PMID: 9608881

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