Article
Expression of costimulatory molecules on alveolar macrophages in hypersensitivity pneumonitis.
American journal of respiratory and critical care medicine - 1 Jun 1999
Israël-Assayag E, Dakhama A, Lavigne S, Laviolette M, Cormier Y
Abstract excerpt
To verify whether alveolar macrophages (AM) of patients with hypersensitivity pneumonitis (HP) increase their antigen-presenting capacity by upregulating the expression of B7 costimulatory molecules (CD80, CD86), and whether a viral infection enhances this expression whereas cigarette smoking abrogates it, we performed bronchoalveolar lavage (BAL) on 18 patients with HP; 10 asymptomatic, virus-exposed subjects...
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