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Liposomes of phosphatidylcholine and cholesterol induce an M2-like macrophage phenotype reprogrammable to M1 pattern with the involvement of B-1 cells.

Immunobiology - 1 Jun 2014

Cruz-Leal Yoelys, Lucatelli Laurindo María Fernanda, Osugui Lika, Luzardo María Del Carmen, López-Requena Alejandro, Alonso María Eugenia, Álvarez Carlos, Popi Ana Flavia, Mariano Mario, Pérez Rolando, Lanio María Eliana

Abstract excerpt

Macrophages respond to endogenous and non-self stimuli acquiring the M1 or M2 phenotypes, corresponding to classical or alternative activation, respectively. The role of B-1 cells in the regulation of macrophage polarization through the secretion of interleukin (IL)-10 has been demonstrated. However, the influence of B-1 cells on macrophage phenotype induction by an immunogen that suppress their ability to...

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PMID: 24594322
DOI: 10.1016/j.imbio.2014.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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