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Article

Innate and adaptive immune functions of peyer's patch monocyte-derived cells.

Cell reports - 5 May 2015

Bonnardel Johnny, Da Silva Clément, Henri Sandrine, Tamoutounour Samira, Chasson Lionel, Montañana-Sanchis Frederic, Gorvel Jean-Pierre, Lelouard Hugues

Abstract excerpt

Peyer's patches (PPs) are primary inductive sites of mucosal immunity. Defining PP mononuclear phagocyte system (MPS) is thus crucial to understand the initiation of mucosal immune response. We provide a comprehensive analysis of the phenotype, distribution, ontogeny, lifespan, function, and transcriptional profile of PP MPS. We show that monocytes give rise to macrophages and to lysozyme-expressing dendritic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25921539
DOI: 10.1016/j.celrep.2015.03.067

Genes

TLR7
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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