Article
Genetic dissection of systemic lupus erythematosus.
Current opinion in immunology - 1 Dec 1999
Wakeland E K, Wandstrat A E, Liu K, Morel L
Abstract excerpt
Recent progress towards elucidating the genetic basis for susceptibility to systemic lupus erythematosus (SLE) has provided insights into the manner in which individual susceptibility genes contribute to disease pathogenesis. Studies in animal models of systemic autoimmunity suggest that genes in three separate pathways contribute to the initiation and progression of systemic autoimmunity. Linkage studies in...
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