Article
An update on genetic studies of systemic lupus erythematosus.
Current rheumatology reports - 1 Aug 2002
Tsao Betty P
Abstract excerpt
Systemic lupus erythematosus (SLE) is a complex, multifactorial autoimmune disease. Genetic factors are thought to contribute to its pathogenesis. There have been numerous recent advances in the study of murine and human lupus genetics. In well-defined experimental transgenic or gene-knockout mouse models, the development of lupus-like disease has implicated specific genes and pathways in the disease...
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