Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spatially specific expression of Hoxb4 is dependent on the ubiquitous transcription factor NFY.

Development (Cambridge, England) - 1 Aug 2002

Gilthorpe Jonathan, Vandromme Marie, Brend Tim, Gutman Alejandro, Summerbell Dennis, Totty Nick, Rigby Peter W J

Abstract excerpt

Understanding how boundaries and domains of Hox gene expression are determined is critical to elucidating the means by which the embryo is patterned along the anteroposterior axis. We have performed a detailed analysis of the mouse Hoxb4 intron enhancer to identify upstream transcriptional regulators. In the context of an heterologous promoter, this enhancer can establish the appropriate anterior boundary of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCAAT-Binding Factor
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryonic and Fetal Development

Share to Enhancer Elements, Genetic

Share to Erythroid-Specific DNA-Binding Factors

Share to Genes, Homeobox

Share to Sequence Homology, Nucleic Acid

Share to YY1 Transcription Factor

Source

Identifiers

PMID: 12135926
DOI: 10.1242/dev.129.16.3887

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spatially specific expression of Hoxb4 is dependent on the ubiquitous transcription factor NFY.PMID 12135926Read ↗

Stereospecificity and PAX6 function direct Hoxd4 neural enhancer activity along the antero-posterior axis.Semantic proximity Read ↗

Transcription factor NFY globally represses the expression of the C. elegans Hox gene Abdominal-B homolog egl-5.Semantic proximity Read ↗

HOXB7 expression is regulated by the transcription factors NF-Y, YY1, Sp1 and USF-1.Semantic proximity Read ↗

Elements both 5' and 3' to the murine Hoxd4 gene establish anterior borders of expression in mesoderm and neurectoderm.Semantic proximity Read ↗

A study of mesoderm patterning through the analysis of the regulation of Xmyf-5 expression.Semantic proximity Read ↗

Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain.Semantic proximity Read ↗

Modulation of chromatin boundary activities by nucleosome-remodeling activities in Drosophila melanogaster.Semantic proximity Read ↗

NF-Y antagonizes renin enhancer function by blocking stimulatory transcription factors.Semantic proximity Read ↗

YY1 acts as a transcriptional activator of Hoxa5 gene expression in mouse organogenesis.Semantic proximity Read ↗

Gata3 directly regulates early inner ear expression of Fgf10.Semantic proximity Read ↗

Hoxa5 gene regulation: A gradient of binding activity to a brachial spinal cord element.Semantic proximity Read ↗

Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.