Article
Hoxa5 gene regulation: A gradient of binding activity to a brachial spinal cord element.
Developmental biology - 1 Apr 1999
Nowling T, Zhou W, Krieger K E, Larochelle C, Nguyen-Huu M C, Jeannotte L, Tuggle C K
Abstract excerpt
The Hox genes cooperate in providing positional information needed for spatial and temporal patterning of the vertebrate body axis. However, the biological mechanisms behind spatial Hox expression are largely unknown. In transgenic mice, gene fusions between Hoxa5 (previously called Hox-1.3) 5' flanking regions and the lacZ reporter gene show tissue- and time-specific expression in the brachial spinal cord in day...
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