Article
HOXB7 expression is regulated by the transcription factors NF-Y, YY1, Sp1 and USF-1.
Biochimica et biophysica acta - 15 Apr 2003
Meccia Ettore, Bottero Lisabianca, Felicetti Federica, Peschle Cesare, Colombo Mario P, Carè Alessandra
Abstract excerpt
Products of HOX genes are transcription factors responsible for developmental regulation and postnatal tissue homeostasis. Besides their well-established function played during embryonic development, we had previously demonstrated the direct role of HOXB7 in tumor progression through transactivation of several genes involved in the proliferative and angiogenic processes. This role is at first exerted through the...
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