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Article

Altered mitogen-activated protein kinase activation in vascular smooth muscle cells from spontaneously hypertensive rats.

Clinical and experimental pharmacology & physiology - 1 Jul 2002

Kubo Takao, Ibusuki Takahiro, Chiba Satoshi, Kambe Toshie, Fukumori Ryuji

Abstract excerpt

1. We previously reported that activation function of mitogen-activated protein kinases (MAPK) is enhanced in aorta strips from both prehypertensive and hypertensive spontaneously hypertensive rats (SHR) and that this enhancement of MAPK activation results from enhanced MAPK activation reactivity to angiotensin (Ang) II in SHR aorta strips. 2. The purpose of the present study was to examine whether the enhanced...

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Identifiers

PMID: 12060094
DOI: 10.1046/j.1440-1681.2002.03694.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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