Article
[A study of DNA polymerase beta mutation in human esophageal cancer].
Zhonghua yi xue za zhi - 1 Jul 2002
Dong Ziming, Zhao Guoqiang, Zhao Qin, Yang Hongyan, Xue Lexun, Tan Xiaohui, Zheng Naigang
Abstract excerpt
OBJECTIVE: To investigate whether DNA polymerase beta (POLB) gene mutations occur in esophageal cancer. METHODS: Thirty specimens of esophageal squamous epithelial cancer were resected during operation. A piece of cancer tissue and a piece of juxtacancerous tissue were taken from each specimen. Fourteen specimens of preinvasive esophageal carcer were obtained by esophagoscopy. Reverse transcription polymerase...
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