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Article

DNA polymerase β mutations and survival of patients with esophageal squamous cell carcinoma in Linzhou City, China.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014

Li Min, Zang Wenqiao, Wang Yuanyuan, Ma Yunyun, Xuan Xiaoyan, Zhao Jimin, Liu Lulu, Dong Ziming, Zhao Guoqiang

Abstract excerpt

Linzhou City in northern China has a high incidence of esophageal squamous cell carcinoma (ESCC). This study retrospectively analyzed the data of 231 cases with ESCC collected from 1998 to 2012. Mutations of DNA polymerase β (polβ) gene in the ESCC samples from patients in Linzhou City were examined by amplifying polβ cDNA by RT-PCR followed by cloning and sequencing. Mutations in polβ were found in 105 cases...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23959474
DOI: 10.1007/s13277-013-1077-4

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