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Article

DNA polymerase β promoter mutations and transcriptional activity in esophageal squamous cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013

Li Min, Zang Wenqiao, Wang Yuanyuan, Li Yuebai, Ma Yunyun, Wang Na, Tang Yue, Liu Lulu, Dong Ziming, Zhao Guoqiang

Abstract excerpt

The present study analyzed the correlation of DNA polymerase β (DNA polβ) promoter mutations and activity in esophageal squamous cell carcinoma (ESCC). The DNA polβ promoter was amplified from 108 ESCC samples and adjacent paracancerous samples by PCR and cloned into the pGL3-enhancer luciferase vector. The recombined vectors were transfected into esophageal carcinoma cells (EC9706, Eca109, and KYSE30), and...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Enzymologic

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Identifiers

PMID: 23749489
DOI: 10.1007/s13277-013-0898-5

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