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Article

Frequent mutation related with overexpression of DNA polymerase beta in primary tumors and precancerous lesions of human stomach.

Cancer letters - 18 Mar 2005

Tan Xiao-Hui, Zhao Min, Pan Kai-Feng, Dong Ying, Dong Bin, Feng Gui-Jian, Jia Guang, Lu You-Yong

Abstract excerpt

To explore whether DNA polymerase beta (pol beta) contributes to the malignant transformation of gastric mucosa, we examined pol beta in gastric tumor cell lines, primary tumors and precancerous lesions. Point mutations of pol beta were detected in 6 of 13 cell lines and 23 of 104 tissues includi...

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Identifiers

PMID: 15737693
DOI: 10.1016/j.canlet.2004.07.049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15737693-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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